Research in the McFarlane group is focused on applying our unique understanding of distinct aspects of genome stability and early human development to identify factors that can be applied to the development of new oncology therapeutics and biomarkers, particularly for early-stage disease.
Figure showing the distribution of an oncogenic factor identified in our group (red) in primary colorectal cancer tissue (tissue stained with DAPI – blue).
Figure showing two focal regions of an oncogenic factor (stained red) within the nucleus of a healthy developmental progenitor cell (stained green), with the blue colour showing the DNA of the cells in this developmental tissue.